直到Vosoritide的获批,才让ACH治疗迈入一个全新的靶向治疗时代。它是一种C型利钠肽(CNP)类似物,通过结合NPR-B进而降低FGFR3的活性来促进生长。临床结果试验显示:相较于安慰剂,每日皮下注射15 μg/kg的Vosoritide,受试者平均年身高增加了1.57厘米。
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Some of the later generations of Pokémon (well, later by the standards of someone who started playing in the 90s) introduced a bunch of little freaks who are more or less just mundane, inanimate objects with faces. These are some of my favorite Pokémon because it feels like whoever designed them was just glancing around the room, looking for anything they could anthropomorphize.
The other big stories (and deals) this morning